Good things may come at a price, but with Perlane it’s a small price to pay to look your very best. Droopy brows, saggy skin, wrinkles and folds–Perlane can handle it all! Since its launch in the year 2000, Perlane has garnered a name for itself in medical beauty. Today it is one of the most effective dermal fillers available, with hundreds of thousands of satisfied users the world over.

Perlane is administered by injecting into the skin with an ultrafine needle. Formulated with hyaluronic acid (which is a naturally-occurring substance in the body,) Perlane is a clear gel that lifts and fills wrinkles and folds to give fuller cheeks and smoother, more defined areas around the eyes, nose and mouth. The results are visible almost immediately. Its effectiveness is derived from an advanced formulation, which depends on chemical ‘cross-links’ designed to withstand the effect of enzymes and delay breakdown of the gel once in the skin. The result is more volume all around, and may last for up to six months, with no harmful traces or residues left over in the body.

Perlane is completely safe and proven to be so in multiple clinical trials. There are no allergic reactions and side-effects are minimal. When side effects are seen, they are usually very mild and go away in a few days. And because it’s non-animal-based, there is virtually no chance of disease transmission.

Blue’s Perlane treatments are high-end procedures performed at our ultramodern Sherman Oaks facility, equipped with the latest technology solutions in medial beauty and wellness. If you’ve been left feeling a little worn and weathered, we can bring back the radiance in your smile and vivacity in your eyes with one of the most effective anti-wrinkle treatments there is. And with the skill and precision of our trained technicians, you’ll walk out feeling like a million dollars!


Check out these real results from real people.


$600 per syringe

Price includes complimentary numbing cream and/or lidocaine injection.


What is Perlane used for?

Perlane is used to smooth moderate to severe facial folds and wrinkles such as the lines from the nose to the corners of the mouth (nasolabial folds). Perlane generally lasts for about 6 months. It has been found to be a safe dermal filler that restores volume and fullness to the skin.

How does Perlane® work?

Perlane is injected into the skin with an ultra-fine needle. It plumps the skin to smooth away wrinkles and folds. Perlane ’s water-loving nature attracts and binds water molecules to help maintain volume. Perlane is composed of hyaluronic acid, a natural substance that already exists in the body. The hyaluronic acid in Perlane is a crystal clear gel that is chemically cross-linked (the long chemical strands are tied together) to delay breakdown by skin enzymes. Perlane is non-animal-based and free from animal protein. This quality prevents disease transmission. Allergy pre-testing is not necessary.

How long does Perlane last?

Perlane is proven to deliver long-lasting results. Studies have shown that Perlane effects generally last about six months as shown in the following graphs. Perlane gradually disappears from the body without a trace.

Is Perlane safe?

Perlane has been used safely by dermatologists and plastic surgeons since 2000 worldwide. Perlane was studied in multiple clinical studies resulting in high patient satisfaction. Side effects were mild. Most of the side effects went away in seven days. Perlane did not cause allergic reactions.

Who should not use Perlane?

Perlane should not be used by people with previous bad allergies (particularly to certain microorganisms known as gram positive bacteria), to drugs that have required in-hospital treatment, or in people with bleeding disorders. Perlane should not be injected anywhere except the skin or just under the skin.

What are some warnings to consider?

The use of Perlane at sites with skin sores, pimples, rashes, hives, cysts, or infections should be postponed until healing is complete. Use of Perlane in these instances could delay healing or make your skin problems worse. You may experience skin discoloration (bruising), swelling, redness, tenderness, pain, itching, or small lumps in the area where you are injected. If any of these events occur, the majority usually last less than seven days. If any symptom lasts longer than two weeks, call the doctor who administered the Perlane injection. Inflammatory papules (red or swollen small bumps) may rarely occur. You may need antibiotics to treat them.

What are some risks that may be experienced?

As with all procedures like this, the injection of Perlane carries a theoretical risk of infection and formation of scar tissue. The safety and effectiveness of Perlane have not been established in the treatment of lips, in nursing mothers, and in patients under 18 or over 65 years of age. Perlane use in nursing could harm you or the nursing child. The use of Perlane in African-American patients can result in hyperpigmentation (darkening of skin color), which may take several weeks to correct. If you have had herpes before, an injection can cause the herpes to come back. The safety of Perlane used with other skin therapies such as laser, mechanical or chemical peeling, and hair removal has not been established. The use of Perlane in these skin therapies may not work or they may damage your skin. You should avoid exposing the area(s) treated with Perlane to excessive sun or UV lamps, and extreme heat and cold until any redness or swelling has disappeared.

What are the major side effects?

Rarely, the doctor may inadvertently inject the product into a blood vessel, which can cause injury to the blood supply and damage to the skin. Rarely, a few people have developed infections of the gel that must be treated with antibiotics or other treatment. Infection of the gel may be hard to treat, but will always go away when the gel is absorbed.

What should patients do prior to treatment?

Perlane requires no pretesting, but you should take a few precautions before being treated. Avoid using St. John’s Wort, high doses of Vitamin E supplements, aspirin, and other non-steroidal anti-inflammatory medications, such as ibuprofen prior to treatment, because these may increase bruising or bleeding at the injection site. Also, if you have previously suffered from facial cold sores, discuss this with your physician. He or she may consider prescribing a medication to minimize recurrence.

Do Perlane injections hurt?

Perlane is injected directly into the skin in tiny amounts by an ultra-fine needle. To help maximize your comfort, you should discuss the use of numbing medicines with your doctor before treatment.

How much do Perlane treatments cost?

Perlane is a customized procedure based on your specific needs, so the cost will vary from patient to patient. In general, the cost of Perlane is comparable to the cost of similar procedures. Because Perlane is long lasting, it may prove to be very economical over the long term. Please ask your doctor to give you an estimate of the cost.

What should I call my doctor about after the treatment?

Most side effects like bruising, swelling, pain, tenderness, redness, and itching will usually go away within a week. Call your doctor if you have persistent problems beyond 14 days. Blisters or skin sores may signal that you are having a recurrent herpes infection that should be treated. You can develop an infection that should be treated with antibiotics. If you experience redness, tenderness, and pain that does not go away you should call your doctor.

What is the dose of Perlane ?

The amount used depends on your face and what you would like to have treated. The average patient who has all of the severe wrinkles around the mouth corrected will use less than half of a tablespoon.

Pre + Post Care

Before Treatment

No anti-inflammatory drugs (Ibuprofen, Motrin, Advil, Aleve, Vioxx, etc.), aspirin, high doses of Vitamin E, or Ginko Biloba one week prior to treatment. This will reduce the possible side effects of bruising and/or swelling in the treated area(s).
Consumption of alcoholic beverages prior to treatment can increase the chances of bruising and/or swelling.
You cannot be pregnant or breastfeeding to receive treatment.
If you have a history of oral herpes, you must pre-treat with an anti-viral three days before your scheduled visit.

After Treatment

Swelling, redness, and tenderness will occur after your treatment and usually resolves within 72 hours.
Cold compresses (a cloth dipped in cold water, wrung out, and applied to the injected area) may be used immediately aftertreatment to reduce swelling.
Avoid touching the treated area within 6 hours of treatment so you do not accidentally injure your skin. After that, the area can be gently washed with soap and water.
Until there is no redness or swelling, avoid exposure of the treated area to intense heat (sun lamp or sun bathing) or extreme cold weather.
If you have suffered previously from facial cold sores, there is a risk that the needle punctures could contribute to another occurrence. Ask your treatment provider about medications that may minimize a recurrence.
Avoid taking aspirin and other non-steroidal anti-inflammatory medications, St. John’s wort, and high doses of Vitamin E supplements for one week after treatment. These agents may increase the risk of bruising and bleeding at the injection site.
Avoid aesthetic lasers, microdermabrasion, or IPL over areas with Perlane for a minimum of one week after treatment.

Follow Up

Follow up treatments should be scheduled usually every six months.
Consistent repeated treatments will produce best resolution of wrinkles.